Disease could be cured within 5 years as scientists make breakthrough discovery
Asthma could become a thing of the past within the next 5 years following a breakthrough discovery by scientists.
According to Telegraph,researchers at Cardiff University and Kings College London identified which cells cause the airways to narrow when triggered by irritants like pollution.
Drugs
already exist which can deactivate the cells and based on this, the
scientists are hopeful that in the future asthmatics take the drug to
prevent an attack ever happening and ending the need to constantly carry
an inhaler.
Speaking on the discovery, Professor Daniela Riccardi, from Cardiff University School of Biosciences described the finding as "incredibly exciting".
She further said:
"If
we can prove that calcilytics are safe when administered directly to
the lung in people, then in five years we could be in a position to
treat patients and potentially stop asthma from happening in the first
place.”
Prior too this, scientists knew that
asthma was caused by inflammation in the small tubes which carry air and
out of the lungs, but did not know what was triggering it.
However
experiments on mice and human airway tissue found that calcium sensing
receptor (CaSR ) cells, which detect changes in the environment, go into
overdrive in asthmatics, triggering airway twitching, inflammation, and
narrowing.
But when calcilytic drugs are inhaled, it deactivates the cells and stops all symptoms.
Scientists
are hoping that clinical trials will begin soon and it is believed that
this new discovery could also pave the way for new treatments for
chronic obstructive pulmonary disease (COPD) and chronic bronchitis, for
which currently no cure exists.
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