Disease could be cured within 5 years as scientists make breakthrough discovery
Asthma could become a thing of the past within the next 5 years following a breakthrough discovery by scientists.
According to Telegraph,researchers at Cardiff University and Kings College London identified which cells cause the airways to narrow when triggered by irritants like pollution.
Drugs
 already exist which can deactivate the cells and based on this, the 
scientists are hopeful that in the future asthmatics take the drug to 
prevent an attack ever happening and ending the need to constantly carry
 an inhaler.
Speaking on the discovery, Professor Daniela Riccardi, from Cardiff University School of Biosciences described the finding as "incredibly exciting".
She further said:
"If
 we can prove that calcilytics are safe when administered directly to 
the lung in people, then in five years we could be in a position to 
treat patients and potentially stop asthma from happening in the first 
place.”
Prior too this, scientists knew that 
asthma was caused by inflammation in the small tubes which carry air and
 out of the lungs, but did not know what was triggering it.
However
 experiments on mice and human airway tissue found that calcium sensing 
receptor (CaSR ) cells, which detect changes in the environment, go into
 overdrive in asthmatics, triggering airway twitching, inflammation, and
 narrowing.
But when calcilytic drugs are inhaled, it deactivates the cells and stops all symptoms.
Scientists
 are hoping that clinical trials will begin soon and it is believed that
 this new discovery could also pave the way for new treatments for 
chronic obstructive pulmonary disease (COPD) and chronic bronchitis, for
 which currently no cure exists.
No comments
Post a Comment